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Rabies: Improvements in diagnosis and epidemiology (Continuation of SE0408, SE0411) - SE0415

Description
This project is targeted specifically at three areas which are of high relevance to MAFF rabies policy.

1) Molecular diagnosis: The quality and speed of molecular diagnosis will be improved by the inclusion of new technology and advanced `in tube` controls. This will deliver diagnostic results quicker and with a greater degree of confidence.

2) Molecular Epidemiology: The existing genetic database will be expanded by the inclusion of more than 400 more virus sequences. This will result in the generation of a powerful epidemiological tool.

3) Serology: An ELISA based serology test will be developed as an alternative to the laborious virus neutralisation tests. This assay will allow large numbers of rabies serology tests to be carried out rapidly in low containment laboratories.
Objective
01 31/07/2000 RT-PCR: Increase the speed of the assay
02 01/03/2000 RT-PCR: Reduce the possibility of cross-contamination.
03 31/03/2002 Molecular epidemiology Expand and develop genetic databases.
04 01/11/2001 Serology: develop alternative serological methods.
Project Documents
• Final Report : Rabies: Improvements in diagnosis and epidemiology (Continuation of SE0408, SE0411)   (93k)
Time-Scale and Cost
From: 1999

To: 2002

Cost: £125,349
Contractor / Funded Organisations
Veterinary Laboratories Agency
Keywords
Animal Health              
Diagnosis              
Epidemiology              
Plants and Animals              
Rabies              
Zoonoses              
Fields of Study
Animal Health