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Complex carbohydrates and insulin sensitivity. - AN0309

Description
This project will establish the acute and chronic effects of varying the intake of complex carbohydrates (starch and non-starch polysaccharides) in healthy adult humans on insulin sensitivity as assayed by the hyperinsulinaemic euglycaemic clamp and the insulin tolerance test. Reduced fat diets will be used and particular attention will be paid to dose: repsonse relationships, dietary compliance and the avoidance of confounding effects eg. alteration in energy intake.
Objective
1. To establish the acute and chronic effects on insulin sensitivity of altering the ration of starch to simple sugars in the diet whilst maintaining fat and protein const ant in normal man. 2. To investigate differences between readily and slowly digestible starch on insulin sensitivity, 3. To establish the chronic effects on insulin sensitivity of increasing the non-starch polysaccharide content of the diet.
Time-Scale and Cost
From: 1995

To: 1997

Cost: £321,045
Contractor / Funded Organisations
University - Newcastle
Keywords