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Development of salmon louse vaccine II - FC0411
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Description
R&D
Summary Objectives:-
Participate in a joint research programme being undertaken
to develop a vaccine to be used to control lice infestations
of farmed salmon. Specifically to attempt to identify
critical target proteins that can be used as antigens,
leading to antibody production in salmon.
Key customer purposes:-
Explore the potential for a salmon louse vaccine as a more
effective and environmentally more acceptable method of
controlling this parasite, thus fulfilling MAFF's duties
under Diseases of Fish Acts.
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Objective
A specific target antigen must be identified for the
development of a recombinant vaccine. To this end we will:
1. Apply monoclonal antibody technology to the
identification of antigens found in the louse gut.
Antibodies will be raised against fractions of louse
antigens and screened by a combination of techniques
including ELISA, immunoblotting and immunohistochemistry.
2. Utilise our DNA libraries in expression vectors in an
attempt to identify clones containing sequences coding for
louse gut antigens. |
Time-Scale and Cost
From:
1991
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To:
1991
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Cost: £24,150 |
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Contractor / Funded Organisations
University - Aberdeen |
Keywords
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Fields of Study
Fish Health and Aquaculture |