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Development of salmon louse vaccine II - FC0411

R&D Summary Objectives:- Participate in a joint research programme being undertaken to develop a vaccine to be used to control lice infestations of farmed salmon. Specifically to attempt to identify critical target proteins that can be used as antigens, leading to antibody production in salmon. Key customer purposes:- Explore the potential for a salmon louse vaccine as a more effective and environmentally more acceptable method of controlling this parasite, thus fulfilling MAFF's duties under Diseases of Fish Acts.
A specific target antigen must be identified for the development of a recombinant vaccine. To this end we will: 1. Apply monoclonal antibody technology to the identification of antigens found in the louse gut. Antibodies will be raised against fractions of louse antigens and screened by a combination of techniques including ELISA, immunoblotting and immunohistochemistry. 2. Utilise our DNA libraries in expression vectors in an attempt to identify clones containing sequences coding for louse gut antigens.
Time-Scale and Cost
From: 1991

To: 1991

Cost: £24,150
Contractor / Funded Organisations
University - Aberdeen
Fields of Study
Fish Health and Aquaculture