Defra - Department for Environment, Food and Rural Affairs.

Science Search

Science and Research Projects

Return to Science Search homepage   Return to Project List

Transmissible Spongiform Encepalopathy (TSE) Strategic Competencies - SE1960

APHA is the National Reference Laboratory for TSE (as defined by EU TSE Regulation 999/2001), and provides advice and consultancy to the UK government departments on TSE issues.

To ensure that this consultancy remains pertinent and responsive, relevant knowledge and practical expertise must be maintained and, where necessary, developed in line with any scientific advances or in response to new/ emerging disease threats , eg previously unidentified strains of agent, or a change in the understanding of the zoonotic potential of specific strains.

This project complements existing surveillance and TSE research with the aim of adding value to both existing and completed projects, effectively communicating all relevant scientific and policy outcomes, and multiskilling the remaining staff to increase the robustness of the specialist and technical core and ensure succession planning of key policy skill areas.
1) Undertake mouse bioassay work to characterise TSE isolates to enhance our ability to detect and appropriately risk assess any unusual new/emerging forms of disease
2) To fill existing gaps on disease phenotype that will inform how TSEs are diagnosed (including how the pathological and clinical presentation of TSEs are shaped by the TSE strain and the host)
3) To investigate diagnostics tests across the spectrum of biochemical, pathological and biological approaches to develop the most robust and appropriate methods for use in statutory applications
Time-Scale and Cost
From: 2015

To: 2016

Cost: £628,201
Contractor / Funded Organisations
APHA (Animal and Plant Health Agency)
Fields of Study
Animal Health