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Development & validation of a method to determine a range of pesticide residues for UK surveillance of foods of animal origin and high fat content. - PS2542

According to Article 29 of Regulation (EC) 396/2005 a community control programme is foreseen for food of animal origin. Until now there are only national control programmes for pesticide residues underway in the Member States.
It is likely that the current proposal of the above Article will become mandatory in 2009.

The proposal detailed in Regulation (EC) 396/2005 includes:

a) Products to be sampled are suggested as butter, ham (smoked or air-dried) and egg (liquid or dried)

b) The pesticides to be analysed are based on Council Directive 86/363/EEC taking into account experiences that have been gained regarding compliance of analytes belonging to the groups of organochlorine, organophosphorous and pyrethroid pesticides.

There are currently 15-20 pesticides, predominantly organochlorine compounds, analysed in samples of animal origin as part of the UK surveillance programme. The new list of analytes in the Regulation (EC) 396/2005 proposal consists of over 50 pesticides, many of which have not undergone full analytical validation to assess the method performance for each component in different commodities.

This project will produce methodology to enable delivery of future UK surveys for the proposed list of over 50 pesticides and assess the financial impact, regarding the funding, of the potential increase in work required to deliver future surveys for food of animal origin.

The project will aim to:

- produce suitable methodology, based on GC-MS techniques, for the determination of over 50 pesticide residues in each sample, maximising the number of pesticides that can be included in one multi-residue method.

- validate the developed methodology for future use in PRC surveillance programs;

- streamline the developed analytical procedures to increase cost efficiency;

- identify which residues can be included in a single multi-residue assay and which require bespoke methods.

If funded, the methodology so derived, will be completed by the end of the 2008 calendar year so that it will be available for the planning of and use in surveys for the PRC 2009 food surveillance programme.

This funding will further extend the use of GC-MS methods used by laboratories currently performing analyses for PRC surveys.
Objective/Milestone 1 - Completed end of month 3

To assess the suitability of using a multi-residue Gas Chromatography with Mass Spectrometry (GC-MS) method for analysis of the compounds listed in Table 1a and 1b. This will focus on the method used at LGC in the current PRC surveillance programme. This initial assessment will categorise the compounds as either;
i) suitable for inclusion in the current multi-residue method, or
ii) unsuitable for inclusion using current procedures, but have potential to be included if procedures are adapted and optimised, or,
iii) unlikely to be includable in a multi-residue method, and likely to require bespoke single-residue methods.

Objective/Milestone 2 - Completed end of month 5

To adapt and optimise the multi-residue extraction method to allow inclusion of those compounds in category (ii) of Milestone 1. Particularly concentrating on the clean-up stages to remove fat from sample extracts.

Objective/Milestone 3 - Completed end of month 5

To produce an interim report to PSD on outputs from Objectives 1 and 2 (i.e. classifying new analytes as multi-residue, or single-residue methods, taking account of the adapted and optimised method). This will allow PSD to make informed cost/benefit decisions on which analytes to include in the 2009 National Surveillance Programme.

Objective/Milestone 4 - Completed end of month 11

To validate the multi-residue method developed as Objective 2 to produce a procedure that will enable the simultaneous detection of the majority of residues in foods of animal origin and/or high fat content as listed in Table 1 and is fit for purpose and ready for use in future PSD surveillance programmes.

Objective/Milestone 5 - Completed end of month 12

To produce a full report to PSD detailing all the results and conclusions of the project, and disseminate the findings to the UK and international scientific community.
Project Documents
• Final Report - SID5A : Development & validation of a method to determine a range of pesticide residues for UK surveillance of foods of animal origin and high fat content.   (2170k)
Time-Scale and Cost
From: 2008

To: 2009

Cost: £50,200
Contractor / Funded Organisations
Agriculture and Food Chain              
Analytical Chemistry              
Food Ingredients              
Food Quality              
Food Safety              
Mass Spectrometry              
Method Development              
Public Health              
Residues Testing              
Fields of Study
Pesticide Safety