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Epidemiology of Cryptosporidium infections in cattle - OZ0408

Objective
OBJ. 1 ESTABLISH OCCURRENCE AND WITHIN-HERD PREVALENCE OF CRYPTOSPORIDIUM SPECIES AND SUBTYPES ON FARMS USING A CROSS SECTIONAL STUDY LINKING SAMPLE COLLECTION TO OD2023.
1.1 Project meeting to design sampling strategy for cross-sectional study. The study will be designed to identify the environmental occurrence, within-herd prevalence and concentration of Cryptosporidium spp. This will provide key information for the data gaps highlighted in the OZ0407 risk model and expert opinion workshop.
1.2 Begin data and sample collection for cross sectional study.
1.3 Begin epidemiological analysis of cross sectional study.
1.4 Provide molecular support to farmed animal and public health outbreak investigations. This will aid identification of risk factors associated with premises linked to cases of human or animal cryptosporidiosis and give added value to the FZ2100 surveillance project.

OBJ. 2 VALIDATE AND HARMONISE MOLECULAR TYPING AT THE SPECIES LEVEL AND FOR INTRA-SPECIES VARIATION.
2.1 Agree DNA extraction and storage procedures for animal and environmental samples.
2.2 Explore and target the most appropriate subtyping techniques for C. hominis and C. parvum for both population genetics studies and rapid methods for outbreak/incident investigations and application to mixed species infections.
2.3 Establish involvement in the NPHS EQA scheme for typing to the species level.
2.4 Perform regular validation exercises with the CRU on the typing methods agreed for use in outbreak investigations.
Project Documents
• EVID4 - Final project report : OZ0408 - Final Report   (670k)
Time-Scale and Cost
From: 2009

To: 2012

Cost: £286,539
Contractor / Funded Organisations
Veterinary Laboratories Agency
Keywords
Animal Health              
Cattle              
Cryptosporidium              
Epidemiology              
Plants and Animals              
Zoonoses              
Fields of Study
Animal Health