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Development of a vaccine to control the poultry red mite & improve laying hen welfare. - AW1138
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Objective
1. Identification of candidate D. gallinae protective antigens, by proteomic and molecular techniques, based on homology with known allergens and protective antigens from other species (Oct 06-Sep 07).
2. Preparation of native candidate antigens and allergens (Jan 07-Dec07).
3. Generation of antibodies and testing in vitro for their ability to affect the viability, fecundity and feeding behaviour of mites (Jan07-Sep08).
4. Generate a D. gallinae cDNA library and immunoscreen with specific antibodies to vaccine candidates; clone and express recombinant versions of these antigens (Jan 07-Mar 09).
5. Evaluate the effect of native and recombinant vaccine antigens on mite numbers, and on the immune response, health and welfare of hens in protection trials (Oct08-Sep 09).
6. Strategy for vaccine commercialisation. (Jul 09-Sep 09).
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Project Documents
• Final Report : Development of a Vaccine to Control the Poultry Red Mite and Improve Laying Hen Welfare
(605k)
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Time-Scale and Cost
From:
2006
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To:
2009
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Cost: £526,986 |
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Contractor / Funded Organisations
Moredun Research Institute, SAC Commercial Ltd |
Keywords
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Fields of Study
Animal Welfare |