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Collection of the biological resources for the identification of surrogate markers for BSE infection in cattle - SE1786

Description
The immune system appears not to be involved combating TSE infection. However, cells of the immune system are involved in the infection process. Changes in the status of these cells may provide early markers for detecting TSE infection. Immune cells are easily accessed by blood sampling and hence provide the ideal material for early diagnosis and disease surveillance. There are currently no high quality, well controlled, fractionated bovine blood derived samples available, which are an essential prerequisite for any study of blood born factors associated with BSE infection. This project will obtain sequential blood samples throughout the time course of disease which will be fractionated into specific cell types and stored for subsequent examination of expression profiles.
Project Documents
• Final Report : Collection of the biological resources for the identification of surrogate   (527k)
Time-Scale and Cost
From: 2003

To: 2008

Cost: £117,069
Contractor / Funded Organisations
Roslin Institute, Edinburgh (BBSRC), Federal Research Centre for Virus Diseases of Animals
Keywords
Animal Health              
BSE              
Cattle              
Diagnosis              
Plants and Animals              
TSEs