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A multi-biomarker approach using the three-spined stickleback as sentinel species: Implementation of genome & proteome analysis - AE1149

Summary Objective
Assess the differences in the expression of genes and proteins by exposing sticklebacks, a widely available and extensively studied fish, to a range of chemicals, either singly or in combination. Determine the feasibility and limitations of using molecular techniques to determine toxicological effects to ecosystems.

Key Customer Purpose
New hazardous substances are continually being considered for prioritisation and risk assessment. Defra protects the marine environment and the outputs will provide potentially novel solutions that help respond to the emerging EU Marine Strategy and data for discussion at OSPAR.

Project Documents
• Final Report : AE1149 Final Report   (7729k)
• Executive Summary : AE1149 Executive Summary   (41k)
Time-Scale and Cost
From: 2003

To: 2006

Cost: £331,276
Contractor / Funded Organisations
Biotech-non GM              
Fields of Study
Environmental Protection - Marine