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The development and use of methods to identify the various actions of dietary complex carbohydrates - AN0302

Description
Since the nutritional significance of dietary complex carbohydrates is now established, a more meaningful measure which is related to function of dietary complex carbohydrates is required. The present methods for measurement are entirely quantitative and provide no insight into their biological potency. The disparate actions of each dietary complex carbohydrate source can be defined in man only by very time consuming and expensive experiments. There is now a need to develop in vitro methods to substantially replace human and animal experiments. Animal experiments will be performed to test the validity of the in vitro methods of assay which have so far only been validated for isolated fibre sources. The experiments will examine the physiscal form of foods and cooking methods and will initially look at cereals, vegetables and fruits eaten in GB.
Objective
To evaluate and develop in vitro models for screening complex carbohydrates for their biological properties, with the aim of reducing the number of time-consuming animal and human experiments and facilitating the design of more precise nutritional studies.
Time-Scale and Cost
From: 1990

To: 1994

Cost: £71,776
Contractor / Funded Organisations
University - Edinburgh
Keywords