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The effects of tallow separation and solvent extraction on PrPsc in the rendering process: a laboratory-scale study - SE0229

Description
A laboratory scale apparatus will be designed and constructed to allow the fate of PrPSc in animal carcase remains to be studied in a simulation of the commercial rendering process employing tallow separation and solvent extraction. The primary objective is to determine whether infectivity titre or the PrPsc molecule itself is inactivated or partitioned during the process.

The exclusion of tallow production from the rendering process in the UK has been held as a major contributory factor in the exposure of the cattle population to TSE infection through contaminated meat and bone meal. It is not clear which part of the process offered protection from the spread of the agent, nor whether this was due to inactivation or partition into the tallow and related extracts.

It is essential to determine whether any of the side products of rendering, such as tallow, contain infectivity and to quantify any partitioning or inactivation that occurs during the process.
Project Documents
• Final Report : The effects of tallow separation and solvent extraction on PrPsc in the rendering process: a laboratory-scale study   (4942k)
Time-Scale and Cost
From: 1999

To: 2004

Cost: £691,624
Contractor / Funded Organisations
Veterinary Laboratories Agency
Keywords
Animal Health              
BSE              
Epidemiology              
Inactivation              
Plants and Animals              
Rendering              
TSEs              
Fields of Study
Animal Health