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Evaluation of the physiological and biochemical responses to altered n-6 and n-3 PUFA intake? Definition of optimal.. - FT0250

Evaluate, in a dose response study, the relative effects of long chain n-3 polyunsaturated fatty acids (EPA/DHA) and the precursor n-3 PUFA, alphalinolenic acid, on a range of health related outcome markers (including fasting and postprandial lipoproteins, blood coagulation and fibrinolytic markers, measures of immune and inflammatory response and antioxidant status). Also to provide a stronger scientific basis for deciding at what level and in what form n-3 PUFA should be provided in the human diet.
To determine the form in which n-3 PUFA should be supplied in the human diet; to determine the optimal amounts of EPA/DHA and ALNA at which beneficial effects on disease markers are observed in the absence of potentially harmful effects; to provide a sound scientific base for advising future nutrition policy and for guiding food manufacturers on the optimum composition of spreads and oils for domestic use and in food manufacture; to assess the potential for, and advisibility of, further expansion in the development of functional foods enriched with EPA/DHA or ALNA.
Time-Scale and Cost
From: 1998

To: 2002

Cost: £215,457
Contractor / Funded Organisations
University - Reading
Food and Drink              
Food Ingredients              
Food manufacturing industry              
Food Quality              
Healthy Eating              
Fields of Study
Resource Efficient and Resilient Food Chain