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A novel method for the detection of MRM products by the identification of bone marrow specific DNA modifications - AN0657

To develop a novel system for the detection of bone marrow which is an indicator of the mechanical recovery process and establish feasibility of the fundamental approach. 1. Develop a control assay system. 2. Identify genes which are expressed differentially in bone marrow and muscle under the control of promoter methylation. 3. Design a PCR which is specific to the original methylation state of the promoter of the selected gene.
Time-Scale and Cost
From: 1996

To: 1998

Cost: £25,700
Contractor / Funded Organisations