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Defining Biomarkers of Different Carbohydrate intakes in populations with varying insulin sensitivity. - AN0311

1.To assess how IGF-1 and IGFBP-1 vary with different levels of insulin sensitivity, determined by glucose tolerance testing. 2.To develop a food frequency questionnaire (FFQ) to assess CHO intake in an Indo-origin population group. 3.To calibrate the FFQ against an assessment of dietary CHO intake using a 7-day food record. 4.To assess how IGF-1 and IGFBP-1, insulin and proinsulin levels vary with different amounts of CHO and different types of CHO - containing foods in the diet; and to determine the usefulness of IGF-1 or IGFBP-1 as a potential marker for CHO intake.
Time-Scale and Cost
From: 1995

To: 1998

Cost: £151,682
Contractor / Funded Organisations
University - Manchester