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Role of faecal diacylglycerols in the aetiology of human colorectal carcinoma. - AN0224

Colorectal carcinoma is the second most common cause of death from cancer in hte UK.
To test the hypotheses that faecal DAG production influences colorectal mucosal cell proliferation and thereby increases the risk of colorectal neoplasia in humans, and that DAG production in the large intestine can be manipulated by varying the lipid composition or other aspects of the diet; and to evaluate the feasibility of developing dietary strategies for the manipulation of faecal DAG production in humans, so as to reduce the risk of colorectal cancer.
Time-Scale and Cost
From: 1994

To: 1997

Cost: £357,965
Contractor / Funded Organisations
IFR - Institute of Food Research (BBSRC)