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Complex carbohydrates and insulin sensitivity. - AN0309
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Description
This project will establish the acute and chronic effects of
varying the intake of complex carbohydrates (starch and
non-starch polysaccharides) in healthy adult humans on
insulin sensitivity as assayed by the hyperinsulinaemic
euglycaemic clamp and the insulin tolerance test. Reduced
fat diets will be used and particular attention will be paid
to dose: repsonse relationships, dietary compliance and the
avoidance of confounding effects eg. alteration in energy
intake. |
Objective
1. To establish the acute and chronic effects on insulin
sensitivity of altering the ration of starch to simple
sugars in the diet whilst maintaining fat and protein const
ant in normal man.
2. To investigate differences between readily and slowly
digestible starch on insulin sensitivity,
3. To establish the chronic effects on insulin sensitivity
of increasing the non-starch polysaccharide content of the
diet. |
Time-Scale and Cost
From:
1995
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To:
1997
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Cost: £321,045 |
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Contractor / Funded Organisations
University - Newcastle |
Keywords
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