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Predicting Reproductive Failure in Frogs using Non-destructive Biomarkers - A Pilot Study - CB0480

World-wide declines in amphibians have been linked to chemical exposure, possibly acting via endocrine-mediated effects on reproduction. The evidence is equivocal however and further research is hampered by the lack of suitable test methods; we only have a destructive technique at present, the detection of intersex in gonadal tissue. Amphibians are used in an OECD test for thyroid sensitive endpoints but suitable tests for reproductive endpoints are not yet validated.

An alternative approach is to use secondary male sexual characteristics such as nuptial pad size and forelimb width to predict effects on physiology and reproductive success.
Time-Scale and Cost
From: 2013

To: 2015

Cost: £139,678
Contractor / Funded Organisations
University of Exeter
Fields of Study
Chemicals and Nanotechnology