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Development of strategies to overcome anti-coagulent resistance in rodents (Joint with PSD - PV0203) - VC0303

Description
VC0303. Strategies to overcome anticoagulant resistance in rodents.

Resistance to anticoagulant rodenticides is increasing in rats. Strategies are needed to overcome further selection of anticoagulant resistance by ensuring best use of current compounds, and identifying rodenticides with alternative modes of action. This study will investigate the theory that vitamin K3 in animal feeds is enhancing the survival and hence selection of anticoagulant resistance in rodents. The study will also aim to develop new rodenticides that will be active against anticoagulant resistant rodents and develop overall strategies to overcome problems caused by anticoagulant resistant rodent populations. Results of the study should increase understanding of the selection of pesticide resistance and how to overcome that resistance. Information on strategies to overcome rodenticide resistance will be published in scientific literature and presented at scientific meetings, as well as being communicated to pesticide manufacturers.
Objective
Investigate the role of vitamin K3 in animal feedstuffs in
enhancing the survival and hence selection of anticoagulant
resistant rodents.

To develop overall strategies to overcome problems caused by
anticoagulant resistant rodent populations.
Time-Scale and Cost
From: 1993

To: 1995

Cost: £160,000
Contractor / Funded Organisations
Central Science Laboratory
Keywords
              
Fields of Study
Wildlife Management