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Extention of current analytical capbility of the UK National Surveillance Scheme to include coccidiostats not currently covered but which have EU MRLs in bovine and poultry liver - VM02172

The European Union requires all member states to implement statutory control systems to protect consumers from residues of veterinary drugs in food. This testing programme includes coccidiostats (medicines used to treat coccidiosis) listed in group B2b of Annex 1 to Council Regulation 2377/90.

A number of veterinary medicines are available for the prevention of coccidiosis in chicken and turkeys. Currently the UK residues statutory surveillance programme includes a multi-residue method that is capable testing for salinomycin, narasin, monensin, lasalocid and nicarbazin in a single analysis (although not all of these compounds are tested in all matrices due to funding constraints of the program).

As part of the planning process for the VMD 2010 statutory surveillance (96/23/EC) programme, incidences of non-compliant samples in both the UK and other EU member states were reviewed. Non-compliant samples for residues of Diclazuril, Maduramycin and Robenidine have been reported to the Commission in 2008. These compounds are not currently included in the scope of the UK scheme. Work to extend the scope of the existing multi-residue screening method to include these compounds as well as halofuginone is already underway and is due to be completed by 31 December 2009. These method changes will not have any impact on the pricing structure for the programme. Initial tests indicate that the inclusion of Toltrazuril in a screening method (as the Toltrazuril sulphone marker residue) will require some additional method modification resulting in a cost increase for each sample tested. Therefore inclusion of this compound may be dependant on the available resources of the scheme.

Analytical methods used to detect veterinary drug residues to check compliance with European legislation must comply with the requirements of Commission Decision 2002/657/EC. This Decision prescribes experimental protocols for determining the performance characteristics of the analytical method, and sets acceptable limits for these performance characteristics.

This proposal is to validate a confirmatory technique for a wide range of coccidiostats in liver including Diclazuril, Maduramycin, Robenidine, Halofuginone and Toltrazuril. Additional compounds such as semduramycin where analytical standards are not currently commercially available will be included if a suitable reference material can be obtained from the Community Reference Laboratory. Performance characteristics will be determined and assessed against the requirements of Commission Decision 2002/657/EC, in order that it can be used for checking that residues comply with European legislation.
Time-Scale and Cost
From: 2010

To: 2011

Cost: £49,511
Contractor / Funded Organisations
Analytical Chemistry              
Analytical Quality Control              
Livestock Farming              
Meat Quality              
Residues Testing              
Fields of Study
Animal Health
Veterinary Medicine