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A study to identify physicochemical facors controlling the capacity of nanoparticles to penetrate cells of the respiratory epithelium, especially those of first contact on inhalation of the particles - CB0407

Description
The objectives of the Project are:
1. Identifying which features of nano-particles/tubes/fibres (NP) are important in particle-cell interactions, considering the potential role of NP chemistry, structure, mass, numbers, shape, surface area, surface charge and surface functionalisation;
2. Suggesting how NPs may be modified to enhance or reduce their capacity to enter cells:
3. suggesting how interactions between NPs and cultured human cells might be studied.
Project Documents
• Final Report : A study to identify physiochemical factors controlling the capacity of nanoparticles to penetrate the cells of the respiratory epithelium   (514k)
• Final Report : A study to identify physiochemical factorscontrolling the capacity of nanoparticles to penetrate the cells of the respiratory epithelium   (350k)
Time-Scale and Cost
From: 2007

To: 2008

Cost: £55,532
Contractor / Funded Organisations
Institute of Occupational Medicine
Keywords
              
Fields of Study
Chemicals and Nanotechnology