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Sustainable production of the natural product, galanthamine - NF0612

Description
The study aims to determine the feasibility of establishing a supply chain for commercially grown daffodil bulbs as raw material for the production of galanthamine, a plant-derived compound used in the treatment of Alzheimer’s disease. A feasibility study will be conducted and a descriptive model of the entire supply chain constructed using proprietary data supplied by the project’s industrial collaborators together with market and scientific data generated within the research programme from a review of the literature. The model will be used to guide the establishment of a robust supply chain for this high value, non-food crop with specific relevance to agricultural production in the less favoured areas (LFA’s) of England and Wales. The project supports Defra policies by considering the development of a supply chain for the sustainable use of a non-food crop as a high value industrial raw material.
Objective
There are three major objectives to this proposal as follows:

1. To conduct a desktop review focusing on the economics, opportunities and constraints for developing a sustainable UK-based supply chain for the plant-derived natural product, galanthamine. Merigan Ltd will have a major role in the conduct of the review.

2. To produce a model of the supply chain to inform the industry about the potential for developing sustainable commercial production of galanthamine in the UK. Merigan Ltd will have a major role in the development of the model and contribute, under objective 1 above, to the conduct of the review.

3. To analyse the levels of galanthamine present in commercially-acceptable daffodil varieties grown on a relevant scale at upland and lowland sites using material provided from Alzeim’s trials. Data from this objective will contribute to inform the review and supply chain model described under objectives 1 and 2 above. IGER will be responsible for the design of these trials and the analysis (identification and quantification) of galanthamine
Project Documents
• Final Report : Sustainable production of the natural product, galanthamine   (285k)
• Final Report - Annex : Sustainable production of the natural product, galanthamine   (9451k)
• Final Report - Annex : Sustainable production of the natural product, galanthamine   (203k)
• Final Report - Annex : Sustainable production of the natural product, galanthamine   (3460k)
• Final Report - Annex : Sustainable production of the natural product, galanthamine   (141k)
Time-Scale and Cost
From: 2005

To: 2006

Cost: £52,274
Contractor / Funded Organisations
Institute of Grassland and Environment Research (IGER)
Keywords
Agri-Industrial              
Arable Farming              
Crops              
Farming              
Fields of Study
Non-Food Crops